Wani bita na baya-bayan nan game da gwajin bazuwar lokaci na III na rigakafin COVID-19 mRNA ya nuna ƙarin haɗarin asibiti ga waɗanda aka yi wa alurar riga kafi idan aka kwatanta da sarrafawa.1 Bayanai daga Hukumar Samar da Kiwon Lafiya ta Sweden (LV) sun tabbatar da cewa allurar rigakafin COVID-19 sun haifar da ƙaruwa daban-daban a cikin tasirin sakamako masu illa, gami da abubuwan da ake zargi da lahani (SSSEs) da mace-mace. Duk da wannan, daidaiton saƙo daga Hukumar Kiwon Lafiyar Jama'a ta Sweden (FoHM) shine fa'idar ta zarce haɗari. Shin shaidun sun goyi bayan wannan ikirari?
Tare da manufar ƙayyade haɗarin ɗanɗano na fuskantar SSSE ciki har da mutuwa, tare da zama asibiti ko mutuwa tare da COVID-19, mun bincika bayanan da ake samu a bainar jama'a daga LV, FoHM, Hukumar Kula da Lafiya da Jin Dadin Sweden (SoS) da Kididdiga Sweden (SCB). Idan aka ɗauka cewa kashi 5% na duk SSSEs an ba da rahotonsu a Sweden, bincikenmu ya nuna cewa rigakafin COVID-19 zai iya amfanar rukuni ɗaya kawai - maza masu shekaru sama da 90. Ga duk sauran ƙungiyoyi, abubuwan da suka faru na SSSE sun wuce haɗarin asibiti da mutuwa tare da COVID-19.
Mu analysis an gudanar da shi a matakai uku. A mataki na daya, mun kiyasta adadin mutane a cikin 100,000 da aka kwantar da su a asibiti ko kuma suka mutu da kamuwa da cutar COVID-19 a cikin shekarar farko ta cutar. Mun fara amfani da bayanai don adadin mutanen da suka shekara 10 zuwa sama waɗanda aka kwantar da su a asibiti tare da (n=81,864) ko kuma waɗanda suka mutu daga (n=12,111, jimlar n=93,975) COVID-19 a asibiti daga Maris 2020, watan farko na kamuwa da cuta, zuwa 3 ga Yuni, 2022, dangane da shekaru da jima'i.2,3 Bugu da kari, a ranar 30 ga Mayu, 2022, n=4,488 mutane sun mutu daga COVID-19 a wani wuri (jimlar n=16,599),4 kuma mun yi zaton cewa duk sun kai shekaru 10 zuwa sama (yaron da ke da shekaru 0-9 ba shi da yuwuwar mutuwa a wajen asibiti). Tun da shekarun da ba a asibiti ba ba a san su ba, mun ɗauki nau'in rarraba shekaru iri ɗaya ga ƙungiyar da ke asibiti, muna ba da lokuta ga ƙungiyoyi masu shekaru daidai.
Don ƙididdige yawan asibitoci da mace-mace tare da COVID-19 a farkon shekarar kamuwa da cuta, Maris 2020 - Fabrairu 2021, mun daidaita jimlar adadin asibitoci da mutuwar mutane masu shekaru 10 da haihuwa har zuwa 3 ga Yuni, 2022 (n=98,463) ta daidai gwargwado a cikin shekarar farko (53.2%, n=51,338) tare da duk wanda ya kamu da cutar COVID-19. Yuni 3, 2022 (n=96,522),3 wanda ya haifar da n=52 370 lokuta masu shekaru 10 da haihuwa. Amfani da yawan jama'a daga Disamba 31, 2020,5 za mu iya ƙididdige adadin masu asibiti da waɗanda suka mutu tare da COVID-19/100,000 a cikin watanni 12 na farko dangane da shekaru da jima'i:
A mataki na biyu, mun ƙiyasta adadin mutanen da suka sami aƙalla SSSE ɗaya a cikin shekarar farko ta rigakafin/100,000 da aka yi musu allurar bisa ga ma'anar LV na wani mummunan lamari:
Ana ɗaukar rahoton da tsanani idan sakamakon da ake zargin yana haifar da mutuwa, yana da haɗari ga rayuwa, ya haɗa da asibiti ko tsawaita asibiti, yana haifar da nakasu, yana haifar da lahani na haihuwa ko wani muhimmin lamari na likita.6
An fara allurar COVID-19 ta Sweden a ranar 27 ga Disamba, 2020. Mu hada da rahotanni of SSSEs har zuwa Disamba 23, 2021. A cikin wannan lokacin, LV ya ɗauka n=8,496 na abubuwan da suka faru marasa kyau da aka ruwaito SSS.7,8,9
Don ƙididdige adadin lokuta na MAB ga kowane mutumin da aka yi wa alurar riga kafi a cikin ƙungiyoyi, mun yi amfani da bayanai daga FoHM.10 A cikin shekarar farko na rigakafin, kashi 85.4% na yawan mutanen da ke da shekaru 12 zuwa sama sun sami aƙalla kashi ɗaya na rigakafin. Koyaya, ba mu da bayanai kan rarraba shekarun da jima'i, amma mun sami damar ƙididdige adadin da aka yi wa alurar riga kafi ta hanyar haɗa adadi na 85.4% tare da bayanai kan adadin da aka yi wa alurar riga kafi a cikin ƙungiyoyin shekaru daban-daban har zuwa Yuni 19, 2022 da daidaitawa don haɓaka ɗaukar rigakafin daga 23 ga Disamba, 2021 zuwa Yuni 19, 2022.10 Dangane da yawan jama'a a Disamba 31, 2021 ta shekaru da jima'i,5 mun sami damar ƙididdige adadin da aka yi wa alurar riga kafi ta ƙungiyar shekaru da jima'i.
tun Bayanai na FoHM sun nuna cewa kusan mata sun fi maza allurar, mun daidaita don wannan a cikin tsari na ƙarshe. - adadin ya karu ga mata kuma ya ragu ga maza don haka rabon matan da aka yi wa allurar ya ninka sau 1.0314 na maza na kowane rukuni. Wannan ya haifar da haka:
A ƙarshe, a mataki na uku, mun ƙididdige adadin SSSE na kowane asibiti ko wanda ya mutu tare da COVID-19. The Rahoton kudi na SSS a Sweden cikakken mulki zama kamar ƙasa kamar 1-2%.11,12 Tunda ba a san ainihin adadin rahoton COVID-19 na SSSEs ba, mun gwada sakamakon ta amfani da ƙimar rahoton 5%, 10% ko 25% na SSSE. Don haka za mu iya kimanta adadin da ya samu aƙalla SSSE/mutum ɗaya da ke asibiti tare da COVID-19, gwargwadon shekaru da jima'i:
Ƙimar> 1 tana ba da shawarar cewa rigakafin COVID-19 yana da illa ga ƙungiyar. Mata da maza masu shekaru 10-79 sun sha fama da SSS musamman. Idan aka yi la'akari da adadin rahoton SSSE na kashi 5%, maza masu shekaru 10-19 ne suka fi fama da rashin ƙarfi, kuma sun sami mafi girma sau 14.1 na SSS fiye da asibiti tare da COVID-19. Don haka, haɗarin rigakafin ya zarce fa'idodin da za a iya samu a yawancin ƙungiyoyi kuma allurar rigakafin kawai ya bayyana yana da amfani ga maza masu shekaru sama da 90. Tsammanin ƙiyasin ra'ayin mazan jiya na adadin rahoton SSSE 25%, haɗarin ya zarce fa'ida ga maza masu ƙasa da shekaru 40 da mata masu ƙasa da 70.
Kodayake mun yi amfani da bayanan da ake samu a bainar jama'a, cikakken saitin bayanan da ake buƙata don tantance fa'idar haɗarin COVID-19 yana samuwa ga hukumomin Sweden kawai. Don amfanin lafiyar jama'a, muna roƙon hukumomi da su gudanar da cikakken fayyace kuma ƙwararrun ƙwararrun nazarin bayanan da ake da su don samar da ingantattun cututtukan cututtuka, mace-mace da nazarin fa'ida.
- Sven Román, MD, Likitan Ƙwararrun Ƙwararrun Ƙwararrun Ƙwararrun Ƙwararrun Ƙwararrun Ƙwararrun Ƙwararrun Ƙwararrun Ƙwararrun Ƙwararrun Ƙwararrun Ƙwararrun Ƙwararrun Ƙwararrun Ƙwararrun Ƙwararrun Ƙwararrun Ƙwararrun Ƙwararrun Ƙwararrun Ƙwararrun Ƙwararrun Ƙwararrun Ƙwararrun Ƙwararrun Ƙwararrun Ƙwararrun Ƙwararru na 2015
- Anette Stahel, MSc a Biomedicine, tsohon mai binciken Cancer a Jami'ar Skövde
- Jonathan Gilthorpe, PhD, Mataimakin Farfesa a Ilimin Halittu, Jami'ar Umeå
- Johan Eddebo, PhD, Mai bincike a Digitalization da Human Rights, Falsafa na Addini, Jami'ar Uppsala
- Niklas Lundström, PhD, MSc a Injiniya Physics, Mataimakin Farfesa a Lissafi, Jami'ar Umeå
Bayanin rikice-rikice na sha'awa: Babu wanda aka bayyana.
References
- Fraiman, J, Erviti, J, Jones, M, Greenland, S, Whelan, P, Kaplan, RM & Doshi, P (2022) Mummunan Al'amuran Mummuna na Sha'awa ta Musamman Biyi rigakafin mRNA a cikin Gwaje-gwajen Rarraba SSRN
- Socialstyrelsen (2022) Kididdiga kan COVID-19 Bayanin hukuma daga SoS
- Socialstyrelsen (2022) Statistik om covid-19; Statistik om avlidna i covid-19 Bayani na hukuma daga SoS Akwai ta hanyar Sven Román a romansven@gmail.com
- Socialstyrelsen (2022) Statistik om covid-19; Statistik om slutenvårdade patienter med covid-19 Bayanin hukuma daga SoS Akwai ta hanyar Sven Román a romansven@gmail.com
- Statistik Centralbyrån (2022) Statistikdatabasen – Folkmängden efter Ålder och Kön År 1860 – 2021 Bayani na hukuma daga SCB
- Läkemedelsverket (2021) Comirnaty - Svenska Handlagda Rapporter om Misstänkta Biverkningar - 2021-11-17
- Läkemedelsverket (2021) Comirnaty - Svenska Handlagda Rapporter om Misstänkta Biverkningar - 2021-12-23
- Läkemedelsverket (2021) Spikevax - Svenska Handlagda Rapporter om Misstänkta Biverkningar - 2021-12-23
- Läkemedelsverket (2021) Vaxzevria - Svenska Handlagda Rapporter om Misstänkta Biverkningar - 2021-12-23
- Folkhälsomyndigheten (2022) Ƙididdiga don rigakafin mot Covid-19; Data som statistiken ovan bygger på kan laddas ner här (excel) Bayanin hukuma daga FHM Akwai ta hanyar Sven Román a romansven@gmail.com
- Jönsson, AK, Jacobsson, I, Andersson, M & Hägg, S (2006) Stor Underrapportering av Hjärnblödning som Läkemedelsbiverkning LT 103(45): 3456-3458
- Rydberg, DM, Holm, L, Engqvist, I, Fryckstedt, J, Lindh, JD et al (2016) Maganganun Magungunan Magunguna a cikin Ward na Kula da Gaggawa na Kulawa na Farko - Yaduwa, Rigakafi da Ba da rahoto PLOS DAYA 11(9): e0162948
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Sven Román yaro ne kuma matashi mai ilimin hauka kuma tun 2015 mai ba da shawara kan ilimin hauka yana aiki a cikin ilimin halin yara da matasa a cikin Sweden. Hakanan yana ɗaya daga cikin likitoci uku waɗanda a cikin Maris 2021 suka kafa Läkaruppropet (Ƙoƙarin Likitoci), martanin Sweden ga Babban Bayanin Barrington, kuma tun daga wannan lokacin wannan roko ya zama ƙungiya mai zaman kanta wacce likitoci, masu bincike, lauyoyi, sauran likitocin kiwon lafiya da masana ilimi ke aiwatar da aikinta, a cikin ruhu ɗaya da Cibiyar Brownstone.
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