Ina roƙon duk waɗanda aka ba ko za a ba ku allurar mura da ku yi la'akari da abubuwan da ke cikin wannan post yayin yanke shawarar ko za ku karɓa.
Mun buga rubuce-rubucen da ke gabatar da shaidar cewa barazanar mura ta tsananta.
Hukumomin Amurka sun san cewa da gaske ana yin zamba, kuma sun koma baya don kare juna da kuma rufe wannan zamba.
Ga kashi na farko na labarin dalilin da ya sa na yi zargin sannan na san game da wannan aƙalla shekaru 25.
A tsakiyar 1990s, yayin da Cochrane Haɗin gwiwar ke farawa, wasu daga cikinmu a cikin Ƙungiyoyin Cutar Cutar Cutar Cutar Cutar da suka fara rubuta ka'idoji don sake duba Cochrane akan batutuwan da suka sha'awar mu (Cochrane kasancewar sa'an nan ƙungiyar sa kai ta ƙasa).
A cikin yanayina, mura ne da sauran magungunan numfashi. Don haka, mun rubuta ka'idoji da kuma sake dubawa game da tasirin (tasiri da lahani) na rigakafin mura (duk nau'ikan da ba a kunna ba da rayuwa) akan yara, manya, masu asthmatics, tsofaffi, da waɗanda ke kula da tsofaffi.
Da farko mun kalli gwaje-gwajen da bazuwar bazuwar sannan mun sunkuyar da matsa lamba don haɗa bayanan lura. An yi gaggawar cire na ƙarshe don kiyaye hankalinmu. Wannan saboda bayanan lura, a wannan yanayin, sun gaya muku komai da akasin sa—ba sabon labari ba.
A ƙarshe an kore ni daga nazarin ilimin asthmatics, amma sauran huɗun an sabunta su akai-akai har sai da muka fahimci cewa babu wata fa'ida a ci gaba, kuma 3 na sake dubawa sun kasance. daidaita (babu ƙarin sabuntawa). Bita guda uku tabbatattu sune:
- Demicheli V, Jefferson T, et al. Alurar rigakafin mura a cikin manya masu lafiya. 2018
- Jefferson T, Rivetti et al. Alurar rigakafin mura a cikin yara masu lafiya. 2018
- Demicheli V, Jefferson T et al. Alurar rigakafi don hana mura a cikin tsofaffi. 2018
- Thomas RE, Jefferson T, et al. Alurar rigakafin mura ga ma'aikatan kiwon lafiya waɗanda ke kula da mutanen da suka kai shekaru 60 ko sama da haka suna zaune a cibiyoyin kulawa na dogon lokaci.
(A halin yanzu ana sabunta bita ta huɗu.)
An ambaci sake dubawa sau dubu da yawa kuma an karanta sau da yawa. Sun haɗa da bayanai daga 105 (ainihin) gwaje-gwajen sarrafa placebo wanda ya shafi mutane sama da 100,000.
To shi ke nan asalinsa. A wannan mataki, za ku yi tambaya: menene?
Don haka menene bazuwar (ainihin) gwajin sarrafa placebo yana ba ku kyakkyawan ra'ayi game da abin da ya faru na mura (a cikin tsofaffin gwaji, ta hanyar haɓakar titres na antibody da ko kuma keɓancewar al'adun gargajiya na hoto). Lokacin da kuka haɗa bayanan tare, ba kuna kallon gwaji ɗaya ko saitin bayanai ba; kuna kallon saitin bayanai da yawa da aka lura kuma aka rubuta a tsayin lokacin "rikicin hunturu".
A cikin bita na babba mai lafiya, hannun placebo ya ɗauki shari'o'i 465 daga cikin mahalarta 18,593. Don haka, daga cikin mutanen da ke da alamun cutar, 97.5% ba su haifar da mura ba. Babu wani gwaji da ya iya gano mace-mace, kuma ba a cika samun kulawar asibiti ba. Gwaje-gwajen sun shafe shekaru 50 na bayanai, don haka muna da duk abubuwan da suka fi girma, masu rauni, da watakila har ma da cututtukan mura guda 2.
Gwaji sune nazarin inda masu bincike zasu iya sarrafa abubuwa, tabbatarwa, da bin diddigin lamura. Abin da ya faru na hannu na placebo yana da mahimmanci don ganin ainihin abin da ke faruwa. Ba a buƙatar samfura. Da muka fara duba tabbatar da mutuwar mura a hannun placebo, mun ga cewa adadin ya kai ɗaruruwa. Matsalolin sun kasance ba kasafai ba; don mace-mace, mun sami zilch - tabbas ba alkaluman da CDC ta gabatar ba, wanda har Anthony Fauci bai yi imani ba. Wannan ya dace da bayanan da muka nuna nan da kuma nan.
Don haka mura ba kasafai ba ne, yawan adadin abubuwan da ke haifar da alamun iri ɗaya, alamun sun taru a ƙarƙashin ma'anar kalmar "mura," kuma ayyukan jama'a kamar allurar rigakafin da ba a kunna ba ba su da wata dama ta murmurewa mai motsi kamar mura. Don haka kuna ganin mummy ta yi gaskiya lokacin da ta saba ce da ni: “Tommy darling, kada ku yi amfani da kalmar F.”
A cikin posts na gaba, TTE zai bayyana yadda kuma dalilin da yasa ƙaddamar da barazanar ke da mahimmanci don kiyaye jikin marasa da'a kamar CDC da UKHSA (Na ambaci waɗannan biyun, amma duk suna a ciki) da kuma nazarin wasu maganganun yaudara da manufofin da suka danganci yaudara da bayanai masu yawa.
Wani tsoho mai zurfafawa ne ya rubuta wannan sakon wanda ya kwashe shekaru talatin yana aiki akan haka kuma yana fatan abubuwan da ke cikin irin wadannan za su zama gadonsa.
Sauran Ayyukan da suka dace
Jefferson T, Di Pietrantonj C, Debalini MG, Rivetti A, Demicheli V. Dangantakar ingancin karatu, concordance, ɗaukar saƙon gida, kudade, da tasiri a cikin nazarin rigakafin mura: nazari na yau da kullun. BMJ 2009; 338 :b354 doi:10.1136/bmj.b354
Jefferson T. Alurar rigakafin mura: manufofin da shaida BMJ 2006; 333 :912 doi:10.1136/bmj.38995.531701.80
Jefferson T, Di Pietrantonj C, Debalini MG, Rivetti A, Demicheli V. Magungunan mura marasa aiki: hanyoyin, manufofi, da siyasa. J Clin Epidemiol. 2009 Yuli; 62 (7): 677-86. doi: 10.1016/j.jclinepi.2008.07.001. Epub 2009 Jan 4. PMID: 19124222.
Doshi P. Shin alkalumman mutuwar mura ta Amurka sun fi PR PR fiye da kimiyya? BMJ. 2005 Dec 10;331(7529):1412.
Doshi P. Influenza: maganin rigakafin cutar ta hanyar talla BMJ 2013; 346:f3037 doi:10.1136/bmj.f3037
An sake bugawa daga marubucin Mayarwa
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Tom Jefferson babban mai koyarwa ne a Jami'ar Oxford, tsohon mai bincike a Cibiyar Nordic Cochrane kuma tsohon mai kula da kimiyya don samar da rahotannin HTA game da marasa magunguna na Agenas, Hukumar Kula da Lafiya ta Yanki ta Italiya.
Duba dukkan posts
