Jamus da Faransa sun yanke shawarar cewa saboda yawan haɗarin myocarditis ya kamata a yi allurar Moderna ba a ba wa mutanen da ba su wuce shekaru 30 ba. Rahotannin labarai sun nuna cewa myocarditis ya ninka sau 5 tare da Moderna fiye da Pfizer a waɗannan shekarun. Ganin cewa akwai Pfizer, jure wa wuce gona da iri na Moderna ga mutane a cikin wannan rukunin zamani a bayyane yake manufofin mara kyau. Don haka Jamus da Faransa sun yanke shawarar da ta dace.
Akwai tasirin manufofin nan da nan ga Amurka, idan muna da ƙarfin hali mu bi su.
Da farko, dole ne Amurka ta fuskanci tambayar: Shin da gaske mun himmatu wajen haɓaka fa'idar da rage illolin allurar rigakafi? A cikin wannan annoba, na yi ƙoƙari don fahimtar shawarar Amurka. Lokacin da muka koyi cewa allurar J&J tana da alaƙa da thrombosis (VITT) musamman a cikin mata
Don haka, dole ne Amurka ta bi sahun Jamus da Faransa nan take. Ba daidai ba ne don ci gaba da gudanar da Moderna ga mutane <30 lokacin da aka san haɗarin wuce gona da iri, kuma akwai madadin mafi aminci. Masanin lafiyar magunguna kuma Farfesa Walid Gellad ya yarda:
Wannan shawarar ta nuna cewa yana yiwuwa a koyi ƙarin bayanan aminci bayan ƙaddamar da samfur wanda zai iya dacewa da amfani da alluran rigakafi don haɓaka fa'ida da rage cutarwa. Yanzu daidaita wannan gaskiyar tare da yaren da ƙwararrun masana da yawa ke amfani da su lokacin da aka ƙaddamar da samfuran, waɗanda ba su da tabbas kuma sun kasa amincewa da rashin tabbas. Ina ba da shawarar sosai cewa mu yi fushi da maganganunmu game da alluran rigakafi tsakanin yara 5 zuwa 11 har sai ƙarin bayanai sun fito.
Matakin yana da tasiri kai tsaye ga ƙoƙarin rigakafin da ke gudana. Ya kamata mu kasance bazuwar mutane, waɗanda suka zaɓa don yin rigakafin, zuwa bambancin kashi da lokacin kashi na 2 don maganin Pfizer. Wannan ya kamata ya faru ga duk wanda ke ƙasa da shekaru 40, musamman ga yara masu shekaru 5 zuwa 11.
Karatun da ke ci gaba yakamata yayi ƙoƙarin ganin idan za'a iya rage yawan guba tare da raguwar kashi ko tsawan lokaci tsakanin allurai. Ba shi da ma'ana kaɗan don haɓaka tsarin kulawa mara kyau, kuma RCTs bayan kasuwa yana yiwuwa a nan. Tare da yara 5 zuwa 11, akwai rashin tabbas game da illolin (akwai lahani, amma kuma ba za a samu ba - ba mu sani ba).
Gwajin bambance-bambance a cikin kashi da jadawali yana da ma'ana. Tuni yara miliyan 1 (5 zuwa 11) sun sami kashi 1. Za a iya yin gwaji a tsakanin mahalarta masu son rai da bazuwar wasu mutane don samun kashi 2 akan jadawalin (kwanaki 21), wasu a ranar 60, wasu a ranar 180, wasu kuma na iya barin kashi 2 gaba ɗaya, kuma cikin watanni za mu san wace dabara ce mafi kyau.
Abin ban mamaki, rashin gudanar da gwaji irin wannan gwaji ne na gaske. Yana nufin za mu ci gaba da babban yaƙin neman zaɓe ba tare da ɗan ra'ayi ba idan an inganta adadin mu da lokacin mu don ma'aunin fa'ida/ cutarwa.
Muna buƙatar ganin matakan troponin da MR na zuciya da aka yi akan masu karɓar rigakafin bazuwar 10,000 a kowane zamani don rubutawa idan akwai myocarditis na subclinical. Muna buƙatar bin diddigin lokaci mai tsawo a kan marasa lafiya da ke fama da myocarditis don ganin ko juzu'i (ko da ƙarami) yana tasowa na dogon lokaci.
Turai ta yi ƙarancin kurakurai marasa ƙarfi fiye da Amurka. Ba su rufe yara masu shekaru 2 ba tare da bayanai ba; Sun kasance (kuma har yanzu) sun fi jinkirin yi wa matasa alurar riga kafi, kuma suna ɗaukar myocarditis da mahimmanci. Muna da abubuwa da yawa da za mu koya daga gare su kan yadda za mu daidaita tasirin miyagun ƙwayoyi tare da aminci.
An karbo daga marubucin blog.
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Vinay Prasad MD MPH masanin ilmin jini-oncologist ne kuma Mataimakin Farfesa a Sashen Cutar cututtuka da Biostatistics a Jami'ar California San Francisco. Yana gudanar da dakin gwaje-gwaje na VKPrasad a UCSF, wanda ke nazarin magungunan ciwon daji, manufofin kiwon lafiya, gwajin asibiti da mafi kyawun yanke shawara. Shi marubucin sama da labaran ilimi 300, da kuma littattafan Ƙarshen Juyawar Likitanci (2015), da Malignant (2020).
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