Bidiyoyin “Veritas” masu ban mamaki waɗanda suka yi tashe-tashen hankula akan Twitter babu shakka sun ƙara rikitar da jama'a. Amma ainihin mai haɓakawa kuma mai abin da ake kira "Pfizer" rigakafin Covid-19 shine kamfanin Jamus BioNTech. Fasahar mRNA mai tushe ta BioNTech ce kuma - tsammanin hakan yana faruwa kwata-kwata - idan wani kamfani yana canza mRNA don ɓoye nau'in ƙwayar cuta ta gida, to ya zama BioNTech.
Duk da haka, kamar yadda aka tattauna a cikin labarin labarina na ƙarshe, kodayake Shugaban Kamfanin BioNTech Ugur Sahin ya yi ikirarin a cikin littafin Alurar rigakafin cewa BioNTech ta kaddamar da aikin rigakafinta na Covid-19 a ranar 27 ga Janairu, 2020, mun san wannan ba gaskiya ba ne: wani rahoton binciken BioNTech da aka fitar a matsayin martani ga bukatar FOIA ya nuna cewa kamfanin ya riga ya fara gwajin gwajin (dabba) a ranar 14 ga Janairu.
Wannan tuni ya zama abin mamaki sosai, tun daga ranar 14 ga Janairu, 2020 makonni 2 ne kawai bayan rahoton farko na shari'ar Covid-19 a Wuhan. A wannan ranar, haka ma, WHO tana cewa babu “tabbatacciyar shaida” na yada mutum-da-mutum. (Dubi WHO tweet nanMe ya sa a duniya BioNTech za ta fara aiki a kan rigakafin Covid-19 ba tare da bayyananniyar shaidar watsa mutum-da-mutum ba?
A wannan lokacin, Pfizer baya cikin aikin rigakafin C-19 na BioNTech. Kamar yadda aka ruwaito a cikin Alurar rigakafin, ƙaramin kamfani na Jamus, wanda bai taɓa samun wani samfuri a kasuwa ba, kawai ya sami nasarar ɗaukar ƙungiyar Amurka da yawa a matsayin abokin tarayya bayan watanni uku (shafi na 156).
Don haka, mun san cewa BioNTech ya fara gwajin gwaji a ranar 14 ga Janairu. Amma, ba shakka, wannan yana nufin cewa dole ne a ƙaddamar da aikin kamar haka. ko da a baya. Dole ne a fara samar da samfurin da ake gwadawa. A wannan yanayin, wannan yana nufin kera mRNA da farko sannan a ƙirƙira shi a cikin nanoparticles na lipid.
Kamar yadda aka taɓa shi a labarina na ƙarshe, wannan shine ainihin manufar binciken: don gwada aikin BioNTech mRNA wanda aka tsara a cikin lipids wanda kamfanin Kanada Acuitas ya yi. Har yanzu BioNTech bai sami damar kera rikodin mRNA ga kowane nau'in ƙwayar cuta ta SARS-CoV-2 ba - an buga cikakken kwayar halittar a ranar da ta gabata - kuma a maimakon haka ta yi amfani da mRNA na ɓoye don antigen (luciferase).
Don haka tsawon wane lokaci za a ɗauka kafin a shirya tsarin gwaji? Abin godiya, littafin Sahin, wanda matarsa Özlem Türeci da ɗan jarida Joe Miller suka rubuta, ya ba da cikakkun bayanai na fasaha da dabaru. A cewar littafin, kera mRNA - tsari da ya ƙunshi "dubban matakai" (shafi na 182) - yana ɗaukar kwanaki biyar (shafi na 170 da 171).
Kwanaki biyar ya kawo mu a ranar 9 ga Janairu. Amma har yanzu ana nannade mRNA a cikin lipids, kuma wannan ya ƙunshi wata matsala ta kayan aiki: BioNTech ba ta iya yin hakan da kanta a hedkwatarta a Mainz, Jamus.
BioNTech yana da nata lipids na cikin gida, amma an same su ba su dace da manufa ba. Don samun mRNA a nannade cikin Acuitas lipids, mRNA dole ne a aika zuwa wani ɗan kwangila na Austriya mai suna Polymun a wajen Vienna.
An yi jigilar mRNA da mota - tuƙi na sa'o'i 8, a cewar Sahin da Türeci - sannan Polymun suka ƙirƙira a cikin lipids, sannan aka mayar da tsarin zuwa Mainz. A cikin littafin, Sahin da Türeci sun bayyana wani nau'in mRNA don nazarin dabba na gaba da ake kammalawa a ranar 2 ga Maris, ana jigilar su zuwa Polymun, sannan a dawo Mainz a nannade da lipids a ranar 9 ga Maris (shafi na 116 da 123).
Don haka, wannan yana ƙara ƙarin kwanaki 5, wanda zai kawo mu yanzu zuwa 4 ga Janairu. Amma, kamar yadda ya faru, BioNTech bai gudanar da gwajin dabba da kanta ba. Wannan ma an yi yarjejeniya da shi kuma an gudanar da shi a wuraren gwaji a wasu wurare. A ciki Alurar rigakafin, Sahin da Türeci sun lura cewa binciken farko na farko ya fara ne a ranar 11 ga Maris, kwanaki 2 bayan isar da mRNA mai lipid-encapsulated.
Ƙara wasu kwanaki 2 a cikin tsarin mu ya kawo mu yanzu zuwa 2 ga Janairu. 2 ga Janairu, 2020 ba makonni biyu ba ne, amma kawai. kwana biyu Bayan rahoton farko na Covid-19 a Wuhan a ranar 31 ga Disamba, 2019.
Amma kafin a kera shi, ba lallai ba ne a ce, tsarin da za a gwada shi ne da farko an yi cikinsa kuma an tsara shi; kuma dole ne a yi tuntuɓar Polymun da Acuitas don samun izini da ake buƙata da shirya haɗin gwiwar da ake buƙata. Duk wannan yana ɗaukar lokaci.
Babu wata nisa daga ƙarshe cewa aikin rigakafin Covid-19 na BioNTech dole ne a zahiri an fara shi kafin ma a ba da rahoton wani shari'ar Covid-19! Tambaya a bayyane ita ce: Ta yaya hakan zai yiwu?
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Robert Kogon shi ne sunan alkalami na wani ɗan jarida da ake bugawa da yawa wanda ke yin rubuce-rubuce kan al'amuran Turai.
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