Don fayyace gaskiya da kuma taimaka wa masu karatu su samar da nasu hukunce-hukuncen yuwuwar son zuciya, Mujallolin Fayil na Nature yana buƙatar mawallafa su bayyana duk wata fa'ida ta kuɗi da / ko ba ta kuɗi ba dangane da aikin da aka bayyana. ~ portfolio na yanayi> manufofin edita> bukatun gasa
Wannan labarin wani marubuci ne wanda ya haɓaka ɗaukar rigakafin COVID-19 a tsakanin matasa yayin da ya kasa bayyana mahimman abubuwan da ke gasa (misali, riƙon sa na tallafin bincike mara iyaka daga Pfizer). Wannan kuma labari ne na gazawar mawallafin marubucin Nature Reviews Zuciya don aiwatar da manufar Fayil na Halitta na ayyana-na-gasa-ban sha'awa. A ƙarshe, wannan labari ne na gazawar Nature Reviews Cardiology's tsarin bita-da-bita-da tsara-tsara don gyara son zuciya na marubucin da ke nuna muradin marubucin..
Yayin da nake karanta wani labari mai taken “Myocarditis bayan COVID-19 rigakafin mRNA: abubuwan lura na asibiti da yuwuwar hanyoyin"In Nature Reviews Cardiology, Na lura da rashin nassoshi masu goyan baya ga wasu iƙirarin marubucin, kamar “[W] tare da rigakafin COVID-19, haɗarin rauni na myocardial da myocarditis yana raguwa sau 1,000 a cikin yawan jama'a….” Don wasu da'awar, nassoshi da aka kawo ba su goyi bayan da'awar da aka yi ba. Bugu da kari, sautin labarin ya kasance daya daga cikin himma wajen inganta rigakafin COVID-19; misali, taken sashe yana karanta "Alurar rigakafi: hanyar da za a bi!" Na yanke shawarar bincika ko marubucin yana da abubuwan da ba a bayyana ba. Wannan binciken ya haifar da na gabatar da 28 ga Maris 2023 "labarin magana" ga editocin Nature Reviews Zuciya.
Miƙawa na zuwa Nature Reviews Zuciya (an gyara kadan):
Na rubuta don sanar da masu karatu da masu gyara Nature Reviews Zuciya na mahimmanci, abubuwan da ba a bayyana ba na jagorar marubucin, Stephane Heymans, na "Myocarditis bayan COVID-19 mRNA alurar riga kafi: lura da asibiti da kuma yuwuwar hanyoyin" [1] (Nat. Rev. Cardiol. 19, 75–77 (2022)), labarin Sharhi da aka buga akan layi 9 Disamba 2021. “Sanarwar Da’a” na labarin sharhi na Heymans ya karanta, “Marubuta ba su bayyana wani buri na gasa ba.” Koyaya, bayanin rikice-rikice na Heymans na labarin [2] wanda aka fara bugawa 30 Disamba 2021 (wanda aka ƙaddamar 1 Satumba 2021) ya karanta, "SH ya karɓi kuɗaɗen sirri don shawarar kimiyya daga AstraZeneca, CSL Behring, Cellprothera, Bayer da Merck; da kuma tallafin bincike mara iyaka daga Pfizer." Heymans'LinkedIn profile [3] ya ƙarasa da cewa, "[H] e shawarwari [sic] daban-daban na fasahar kere-kere da kamfanonin harhada magunguna, da kuma manyan kamfanoni da ke neman mafi kyawun saka hannun jari."
Rikicin sha'awa na Heymans yana da alaƙa a fili ga gargaɗin labarinsa na Sharhi kamar "Alurar rigakafi: hanyar da za a bi!" Bugu da ƙari, labarin sharhi na Heymans yana ba da shaida na son zuciya ga marubuci:
- Maganar "Daga cikin marasa lafiya tare da COVID-19, 10% na marasa lafiya da 40% na marasa lafiya da ke asibiti suna da rauni mai mahimmanci na asibiti, galibi idan babu cutar cututtukan jijiyoyin jini na asibiti" ba a goyan bayan bayanan da aka ambata [4], wanda ba ya tattauna rashi na cututtukan jijiyoyin jini; a maimakon haka, ya ce, "Ko da yake ba a fahimci tsarin raunin zuciya da ke da alaƙa da COVID-19 ba, marasa lafiya da ke fama da cututtukan zuciya sau huɗu suna iya haɓaka matakan hs-cTn fiye da waɗanda ba tare da su ba. [hs-cTn = troponin na zuciya mai girma, matakan da aka ɗaukaka suna nuna rauni]."
- Maganar "Har yau, mutuwar takwas kawai ta hanyar COVID-19 mRNA-alurar rigakafin myocarditis an ba da rahoton… (duba ƙarin bayani)" ba ya goyan bayan ƙarin bayanin, jerin nassoshi 159, mafi yawan masu alaƙa da alaƙar rigakafin myocarditis "VAM." Reference 79 yayi rahoton mutuwar 8 Pfizer mRNA VAM (bayanin Hukumar Kula da Magunguna ta Turai), da kuma mutuwar Pfizer VAM guda 2 da Ma'aikatar Lafiya ta Isra'ila ta sanar Afrilu 2021. Rahoton 1, 25, da 147, bi da bi, mutuwar mRNA VAM mai zuwa: 27 mai shekaru 22 namiji, Koriya, Pfizer-42 Namiji mai shekaru 13 (Moderna, Amurka). Don haka, jimillar adadin mutuwar mRNA-VAM da aka ba da rahoto aƙalla 8, ba XNUMX da aka yi da'awar ba.
- Ana kuma amfani da jerin ƙarin bayani don tallafawa da'awar: "A cikin COVID-19 mRNA-alurar rigakafin myocarditis,> 90% na marasa lafiya za su murmure gaba ɗaya gabaɗaya…." Duk da haka, ba a bayyana wace tunani ko rukuni na nassoshi ke ba da tallafi ba. A zahiri, nuni na 79 ya saba wa da'awar, yana ba da rahoton "Ko da yake da wuya, ƙungiyar da aka gano na iya zama mai tsanani kamar yadda aka nuna ta hanyar gano cewa yawancin shari'o'in ba su murmure ba kuma ta hanyar (duk da haka kaɗan) sun mutu." A Nature-Medicine labarin [5], wanda aka buga akan layi 14 Disamba 2021, ya ba da rahoton shari'o'in Pfizer VAM guda 158 (Table 2), tare da 25 wanda ke haifar da mutuwa (Table S1), yana ba da ƙimar rayuwa kusan 84.2% (ba> 90% cikakkiyar farfadowa ba).
- A ƙarshe, ba a bayar da nassoshi masu goyan baya ga wasu ikirari ba, kamar su “[W] da rigakafin COVID-19, haɗarin rauni na zuciya da myocarditis yana raguwa sau 1,000 a yawan jama'a….”
Ƙarshen ƙaddamarwa
A ranar 14 ga Afrilu 2023, Nature Reviews ZuciyaBabban editan Dr. Gregory Lim ya ba ni amsa mai ladabi daga Dr. Heymans ga labarin da na gabatar a cikin labarin wanda Heymans ya amince da "ayyukansa na ba da shawara tare da AstraZeneca da CSL Behring" yayin da ya kasa amincewa da tallafin bincikensa mara iyaka daga Pfizer da kuma kasa magance matsalolin da suka shafi zuba jari a matsayin mai ba da shawara. Dr. Heymans kuma ya amsa maki na harsashi (duba ƙasa). Edita Lim ya ce, "Kamar yadda muke jin cewa Farfesa Heymans ya yi gamsasshen bayani game da ra'ayoyin ku, kuma ba a buƙatar gyara ga labarin Sharhi ba, mun yanke shawarar cewa ba za mu ci gaba da buga Labaran ku ba."
Shin bai kamata manufar bayyanar da sha'awar gasa ba ta tilasta marubucin haɓaka samfurin da Pfizer da AstraZeneca suka samar don bayyana cewa yana da tallafin bincike mara iyaka daga Pfizer kuma yana aiki a matsayin mai ba da shawara ga AstraZeneca? Na yi iƙirarin cewa manufar Fayil ɗin Yanayi yana buƙatar irin wannan bayyanawa. Kafin in tabbatar da wannan iƙirari, duba idan kun yarda da Edita Lim cewa Farfesa Heymans ya yi gamsasshen bayani game da maganganuna.
Bullet Point 1: Dr. Heymans ya mayar da martani ga bullet dina ta farko ta hanyar furtawa "Wasu nassoshi ba su cika bayanin ba [saboda iyakancewar 10 don sharhi]." Koyaya, bayanin da ya bayar [4] bai ko da wani bangare ya rufe da'awarsa cewa marasa lafiya da COVID-19 suna da rauni mai mahimmanci na asibiti "mafi yawa idan babu cutar cututtukan jijiyoyin jini na asibiti." Wannan da’awar bata ce saboda dalilai guda biyu—(i) abin da aka ambata bai yi wannan da’awar ba kwata-kwata; a maimakon haka, (ii) yana nuna akasin haka ne tare da “cututtukan jijiyoyin jini” wanda aka maye gurbinsa da “cututtukan zuciya”.
Bullet Point #2: Dr. Heymans ya amsa
Mun kafa wannan lamba [8 VAM mutuwar da aka ruwaito zuwa yau] a kan littafin mai zuwa, amma tabbas ilimi ya canza tun lokacin, da kuma bayan littafinmu.
Lazaros G, Klein AL, Hatziantoniou S, Tsioufis C, Tsakris A, Anastassopoulou C. Novel Platform of mRNA COVID-19 Vaccines da Myocarditis: Alamun cikin Ƙungiya mai yiwuwa. [wanda aka buga akan layi kafin bugawa, 2021 Jul 13]. maganin. 2021. doi.org/10.1016/j.vaccine.2021.07.016
A cikin bullet dina ban koma ga “ilimi” da ya canza “bayan bugu” ba. Maimakon haka, na yi nuni da bayani a cikin jerin nassoshi na Dr. Heymans! Takamaiman bayanin Dokta Heymans ya ambata (Lazaros et al.) Ya tattauna game da mutuwar 10 VAM (8 a Turai da 2 mutuwar da aka yi da yawa a Isra'ila) kuma, kamar yadda na yi dalla-dalla, jerin sunayen Dr. Heymans ya haɗa da tattaunawa na akalla 3 ƙarin mutuwar VAM. Me yasa Dr. Heymans zai yi fatan rashin bayar da rahoton faruwar mutuwar VAM? Shin zai iya kasancewa da alaƙa da abubuwan da ya fafata a matsayin mai ba da shawara kan masana'antar harhada magunguna kuma a matsayin mai karɓar tallafin bincike mara iyaka daga Pfizer?
Bullet Point #3: Ga martanin Dr. Heymans:
Mun kafa kimar mu [> 90% akan wallafe-wallafe daban-daban. Farfadowar aikin yana nufin aikin zuciya, haɓaka aikin systolic (ɓangaren fitarwa), ba ga adadin abubuwan da suka faru ba. Buga mai ban sha'awa da Dr. Bourdon ke magana a kai, yana da rudani, kamar yadda kuma yake duban abubuwan da suka faru bayan allurar rigakafin a cikin waɗancan marasa lafiya waɗanda aka kwantar da su a asibiti kawai (ƙananan zaɓi), gami da majiyyaci (sic) waɗanda ke da duka allurar da kamuwa da COVID-19.
Ko da a cikin martanin Dr. Heymans, ba mu sami takamaiman nassoshi waɗanda ke goyan bayan kimantarsa na> 90% dawo da aikin daga VAM ba.. Yi la'akari da cewa na ba da nassoshi biyu waɗanda ba su goyi bayan ƙimarsa ba - ɗaya shine tunani (Lazaros et al.) wanda Dr. Heymans ya bayar a cikin [1], wanda ya gano adadin "ba a dawo da shi ba" na 30.6% na Moderna's mRNA-1273 da 33.2% don Pfizer's BNT162b2. Na gane cewa bayanina na biyu ([5]) ba a buga shi ba sai jim kadan bayan [1] ya bayyana.
Game da maganganun Dr. Heymans game da littafin Patone et al. [5]: Ee, abubuwan 158 Pfizer VAM da aka lura a cikin yawan binciken Patone et al. asibiti saboda VAM. Wani bincike-bincike na kwanan nan na 23 binciken rigakafin myocarditis / pericarditis da ke da alaƙa da allurar ciki har da marasa lafiya 854 masu shekaru 12-20 shekaru sun sami kashi 92.6 cikin ɗari na asibiti tare da matsakaicin tsawon kwanaki 2.8 da ƙimar shigar da kashi 23.2 na ICU. Don haka, don daidaitawa don nuna son kai, muna iya kimanta cewa Patone et al.'s 158 Pfizer VAM abubuwan da ke buƙatar asibiti an zana su daga abubuwan 158/0.926≈171 VAM. An sami mutuwar mutane 25 sakamakon waɗannan abubuwan da suka faru (tare da 13 daga cikin abubuwan da suka faru sun kasance hasashe). Wannan yana haifar da ƙimar rayuwa kusan kashi 85.4 (≈171-25/171)*100%); sake, ba> kashi 90 na farfadowar aikin ba. Ko da kashi 70 cikin 90 na asibiti na VAM zai haifar da adadin tsira na ƙasa da kashi 88.9 (kashi XNUMX).
Bullet Point #4: Cikakkar jimlar daga [1] wacce ta haɗa da furucin da Dr. Heymans ya yi maras kyau wanda aka bayyana a cikin harsashi na huɗu yana karantawa, “Bugu da ƙari, tare da rigakafin COVID-19, haɗarin myocardial rauni da kuma myocarditis [wanda ke da alaƙa da kamuwa da cuta] yana rage ninki 1,000 a cikin yawan jama'a, tare da ƙaramar 1-5-ninka ƙara haɗarin m myocarditis a cikin matasa manya [wanda ke da alaƙa da alurar riga kafi]" (bayyana ra'ayoyi masu ma'ana da nau'in ban mamaki da na ƙara). Ga martanin Dr. Heymans:
Wannan bayanin ya samo asali ne daga lissafin da ke biyo bayan wallafe-wallafe. Ɗaukar rauni na myocardial da myocarditis tare bayan kamuwa da cutar COVID (saboda a cikin aikin asibiti troponin haɓaka daga rauni na zuciya saboda rashin lafiya mai tsanani ko myocarditis suna da gabatarwa iri ɗaya), abin da ya faru shine 1000-4000 a cikin 100,000 bayan kamuwa da COVID-19. Abubuwan da ke faruwa na myocarditis / rauni na zuciya shine 1-10 a cikin 100,000 a cikin mutanen da aka yi wa alurar riga kafi. Shi ya sa muka zo ga wannan magana mai ninki 1000. Alurar riga kafi yana da alaƙa akai-akai tare da ƙananan haɗarin manyan cututtukan zuciya mara kyau bayan kamuwa da cutar COVID (1, 2).
A cikin jimloli huɗu na farko na amsarsa, Dr. Heymans ya bayyana yana yin kwatancen apples-to-oranges iri ɗaya wanda ya yi a cikin Tebu 1 na labarin da ya buga [1]:
Sai dai daga Table 1 na [1]
A cikin teburin da ya gabata, Dr. Heymans yana kwatanta haɗarin kamuwa da cuta "myocarditis da ciwon zuciya" to myocarditis hadarin kawai dangane da allurar rigakafi. Ya kamata ko dai ya kwatanta kamuwa da cutar myocarditis mai alaka da kamuwa da cuta da cutar myocarditis mai alaka da alurar riga kafi ko kamuwa da cutar myocarditis-da-cututtukan zuciya (wanda ke nuna alamun haɓakar matakan troponin) zuwa cututtukan cututtukan cututtukan cututtukan ƙwayar cuta da cututtukan zuciya. Ko ɗaya daga cikin waɗannan ingantattun kwatancen (marasa son zuciya) zai nuna ƙima sun yi daidai da (rabo kusan = 1, ba 1,000 ba).
Misali, binciken by Mansanguan et al. ya sami shaidar raunin zuciya (matakan troponin masu girma) biyo bayan Pfizer BNT162b2 a cikin adadin 2,475 a cikin 100,000 da aka yi wa alurar riga kafi (a cikin kewayon 1,000-4,000 wanda Dr. Heymans ya ba da ciwon zuciya bayan kamuwa da cuta). wani binciken by Dr. Christian Mueller (Jami'ar Asibitin Basel) ya gano 22 na 777 mRNA masu karɓa na ƙarfafa kashi sun haifar da mummunan rauni na myocardial (alamar da matakan troponin masu girma), wanda ya dace da adadin 2,831 a cikin 100,000 (tare da mafi girma a tsakanin mata fiye da tsakanin maza). Dangane da myocarditis hadarin bayan kamuwa da cuta, Karlstad et al. (eTable 7) gano haɗarin kamuwa da kamuwa da cutar myocarditis don zama, ga maza 12+, game da 3.69 lokuta a cikin 100,000 cututtuka a cikin kwanaki 28 (lokacin haɗari bayan kamuwa da cuta) da kuma game da 3.42 ga mata 12+. Kwatanta waɗannan ƙididdiga masu alaƙa da kamuwa da cuta zuwa ƙimar VAM da aka bayar a Teburin Dr. Heymans 1: 0.3 zuwa 5 a cikin 100,000 rigakafin.
Lura: Adadin VAM na iya zama da yawa sama da ƙimar myocarditis da ke da alaƙa da kamuwa da cuta; misali, Karlstad et al. gano abin da ya faru na myocarditis (yana buƙatar asibiti) ya zama kamar akwai kusan 18 lokuta masu yawa da 100,000 2nd allurai na mRNA-1273 na Moderna da aka gudanar ga maza 16-24 yayin da adadin da ke da alaƙa da kamuwa da cuta ga maza masu shekaru 16-24 shine 1.37 wuce gona da iri a cikin cututtukan 100,000.
Iyakar abin da Dr. Heymans ya bayar wanda ke da alaƙa da iƙirarin sa na alluran rigakafin samar da raguwar "ninki 1,000" a cikin haɗarin ciwon zuciya na zuciya shine jumlarsa ta ƙarshe, wanda Dr. Heymans ya ba da nassoshi biyu don tallafawa masu zuwa. da yawa mafi ƙanƙantar faɗa: "Alurar riga kafi yana da alaƙa akai-akai tare da ƙananan haɗarin manyan cututtukan zuciya mara kyau bayan kamuwa da cutar COVID (1,2) [(1: Jiang et al, 2: Kim et al.)]":
Jiang J, Chan L, Kauffman J, Narula J, Charney AW, Oh W, et al. Tasirin Alurar riga kafi akan Manyan Mummunan Al'amuran Zuciya a cikin Marasa lafiya Masu Cutar COVID-19. J Am Coll Cardiol. 2023;81 (9): 928-30.
Kim YE, Huh K, Park YJ, Peck KR, Jung J. Ƙungiyar Tsakanin Alurar riga kafi da Ciwon Zuciya da Ciwon Zuciya Bayan Cutar COVID-19. JAMA. 2022;328 (9): 887-9.
Na farko, zan nuna cewa babu ɗaya daga cikin nassoshi na baya da aka samu a lokacin buga labarin Sharhin Dr. Heyman [1]. Jiang et al. An buga akan layi 20 Fabrairu 2023 da Kim et al. An buga shi akan layi 22 Yuli 2022. Mafi mahimmanci shine binciken Jiang et al na "Manyan Abubuwan Ciwon Zuciya" (MACE) biyo bayan kamuwa da cutar COVID-19 baya goyan bayan da'awar Dr. Heymans na hyperbolic na "ninki 1,000" a cikin hadarin ciwon zuciya na zuciya wanda aka samo daga allurar rigakafi.
Jiang et al. gano yawan binciken su na marasa lafiya 1,934,294 (tare da shekaru 45.2 shekaru) cewa cikakken maganin rigakafi yana rage haɗarin kamuwa da cutar MACE ta hanyar daidaita-haɗari-rabo factor na 0.59 ga yawan jama'a yayin da Dr. Heymans ya ba da shawarar da gaske na 0.001 ga yawan jama'a. Park et al. Nemo ma'aunin rage haɗari ya zama 0.42 (ba 0.001 ba).
Layin ƙasa: Dr. Heymans bai bayar da wani tallafi ko kaɗan ba don iƙirarinsa cewa “[W] tare da rigakafin COVID-19, haɗarin rauni na zuciya da kuma myocarditis yana rage sau 1,000 a cikin jama'a. ”… A gaskiya ma, ya ba da nassoshi da ke ba da shawarar kiyasinsa na "raguwar ninki 1,000" don haɓakawa sosai.
Yanzu zan tabbatar da cewa manufar Fayil na Nature-na-gasa-ban sha'awa yana buƙatar Dr. Heymans ya bayyana muradun sa masu gasa.
Gasar Wasanni: Manufar Fatifolio na gasa-sha'awa tana isar da tsammanin mawallafa ta hanyar ma'anoni, gami da masu zuwa:
(1) "An ayyana [C] bukatu masu fa'ida a matsayin buƙatun kuɗi da waɗanda ba na kuɗi ba waɗanda za su iya lalata kai tsaye, ko kuma a fahimce su don lalata haƙiƙa, mutunci da ƙimar ɗaba'ar, ta hanyar tasiri mai yuwuwa kan hukunce-hukuncen marubuta da ayyukan marubuta dangane da haƙiƙanin gabatarwar bayanai, bincike da fassarar."
(2) "Bukatun gasa na kuɗi sun haɗa da ɗayan waɗannan masu zuwa:"
(a) "Kudade: Tallafin bincike (ciki har da albashi, kayan aiki, kayayyaki, da sauran kashe kuɗi) ta ƙungiyoyin da za su iya samun ko rasa kuɗi ta hanyar wannan ɗaba'ar."
(b) "Aiki: Kwanan nan (yayin da ke cikin aikin bincike), gabatarwa ko tsammanin aiki ta kowace kungiya da za ta iya samun ko rasa kudi ta hanyar wannan littafin."
(c) "Bukatun kuɗi na sirri: Hannun jari ko hannun jari a cikin kamfanoni waɗanda zasu iya samun ko rasa kuɗi ta hanyar wallafe-wallafe; kudade shawarwari ko wasu nau'ikan lada (ciki har da biyan kuɗi don halartar taron tattaunawa) daga ƙungiyoyin da za su iya samun ko asara ta kuɗi; haƙƙin mallaka ko aikace-aikacen haƙƙin mallaka (wanda aka bayar ko a jira) waɗanda marubutan ko cibiyoyinsu suka gabatar da ƙimar jama'a.
Dr. Heymans yana da sha'awar kuɗi ta nau'in 2 (a) - tallafin bincike mara iyaka daga Pfizer wanda rigakafin mRNA ya haɓaka a cikin labarin sharhi [1]:
(i) Farkon sakin layi na labarin Dr. Heymans [1] (wanda aka saita cikin nau'in bugun fuska) ya ƙare "Saboda haka, ya kamata a ba da shawarar rigakafin COVID-19 ga matasa da manya."
(ii) Wani sashe na [1] yana karanta "Vaccinations: the way to go!" (kuma an saita shi a nau'in boldface).
Yanzu la'akari da iyakar abin da Pfizer "zai iya samun ko rasa kuɗi ta wannan littafin," inda "wannan littafin" shine labarin Sharhin Dr. Heymans [1]. Binciken rahoton shekara-shekara na Pfizer daga 2021 da 2022 ya nuna hakan na 2021, Pfizer's mRNA COVID maganin alurar riga kafi ya kai sama da kashi 45% na kudaden shigar kamfanin (biliyan 36.781 na biliyan 81.3). Domin 2022, Pfizer's mRNA COVID maganin alurar riga kafi ya kai sama da kashi 37% na kudaden shigar kamfanin (biliyan 37.806 na biliyan 100.33). Ta yaya za a yi tasiri kan layin ƙasa na Pfizer idan Dokta Heymans ya yi tambaya game da fa'idar fa'ida ta fa'idar rigakafin mRNA COVID ga samari maza (16-24, misali) waɗanda ke cikin haɗarin kamuwa da cututtukan myocarditis/pericarditis mai alaƙa?
∙ Dr. Heymans yana da fa'ida mai fa'ida ta kuɗi ta nau'in 2 (b) - aikinsa a matsayin mai ba da shawara ga AstraZeneca.
Yi la'akari da kanun labarai mai zuwa: "AstraZeneca don cin riba daga rigakafin Covid" daga labarin BBC yana bayyana kimanin wata 1 kafin buga labarin Dr. Heymans [1] in Nature Reviews Zuciya.
Bugu da ƙari, 2 (b) ya ambaci “ayyukan da kowace ƙungiya za ta iya samu ko ta yi hasarar kuɗi ta wannan littafin.” Gabaɗaya, mai binciken likita da ke ba da izinin amfani da kowane samfur na magunguna wajibi ne ya bayyana duk wani abin da ya gabata, na yanzu, ko abin da ake tsammani nan gaba ko samun kuɗin shiga daga masana'antar harhada magunguna. Me yasa? Mai bincike da ke sha'awar kiyayewa ko jawo irin waɗannan kudade na iya ƙila ya ƙi buga binciken da ba ya goyan bayan cin samfuran magunguna.
∙ Akwai shaidar cewa Dr. Heymans na iya samun fa'idodi masu gasa na nau'in 2(c).
Dr. Heymans ya yarda a cikin bayanin martabarsa na LinkedIn cewa yana ba da shawarar "kamfanonin jari-hujja masu neman mafi kyawun saka hannun jari." Domin Dr. Heymans yana ba da shawarar zuba jari, dole ne ya yi imani yana da fahimtar kasuwa wanda zai iya amfanar abokan cinikinsa. Idan aka yi la'akari da sha'awar Dr. Heymans, yana da kyau a ɗauka cewa fahimtarsa ta shafi saka hannun jari a masana'antar harhada magunguna. Tambaya mai mahimmanci da ya kamata a yi la'akari: idan abokan ciniki na Dr. Heymans suna da jari a cikin masana'antar harhada magunguna, to shin zai kasance yana biyan bukatun abokan cinikinsa idan ya buga wasu kalamai da zasu iya tasiri ga ribar wannan masana'antar?
Kammalawa: A cikin labarin Sharhi [1], Dr. Heymans ya inganta ɗaukar rigakafin COVID-19 tare da ƙarya, yaudara, mara tallafi, da ƙari da yawa waɗanda ke nuna buƙatunsa masu fa'ida (yin hidima a matsayin mai ba da shawara ga AstraZeneca, da sauran kamfanonin harhada magunguna, suna riƙe da tallafin bincike mara ƙima daga Pfizer, da bayar da shawarar saka hannun jari a cikin masana'antu). Edita Lim ya kasa aiwatar da manufar bayyana fa'ida ta gasa ta Nature Portfolio. Haka kuma, ga labarin Dr. Heymans [1] Nature Reviews ZuciyaTsarin edita- da bita-tsara ya kasa gyara son zuciya na marubuci.
Bayanin Bene: Dokta Joshua Parreco ya yi nuni da marubucin Dr. Heymans Leslie T. Cooper shima yana da muradin gasa da ba a bayyana ba: a cewar OpenPaymentsData.cms.gov, Cooper ya samu a watan Disamba na 2021 kudaden shawarwari daga duka ER Squibb & Sons, LLC da Moderna TX, Inc.
References
1. Heymans, S., Cooper, LT Myocarditis bayan COVID-19 mRNA alurar riga kafi: lura da asibiti da yuwuwar hanyoyin. Sunan mahaifi Cardiol 19, 75-77 (2022). https://doi.org/10.1038/s41569-021-00662-w
2. de Boer RA, Heymans S, Backs J, Carrier L, Coats AJS, Dimmeler S, Eschenhagen T, Filippatos G, Gepstein L, Hulot JS, Knöll R, Kupatt C, Linke WA, Seidman CE, Tocchetti CG, van der Velden J, Walsh R, T. hypertrophic cardiomyopathies: daga tsarin kwayoyin zuwa maƙasudin warkewa. Takardar matsayi daga Ƙungiyar Ƙwararrun Zuciya (HFA) da Ƙungiyar Ƙwararrun Ƙwararrun Ƙwararrun Ƙwararrun Ƙwararrun Ƙwararrun Ƙwararrun Ƙwararrun Ƙwararrun Ƙwararrun Ƙwararrun Ƙwararrun Ƙwararrun Ƙwararrun Ƙwararrun Ƙwararru (ESC). Eur J Zuciyar Zuciya. 2022 Maris; 24 (3): 406-420. doi: https://doi.org/10.1002/ejhf.2414.
3. Stephane Heymans. LinkedIn Mini-Profile. https://be.linkedin.com/in/stephane-heymans-76528284?trk=author_mini-profile_title. An shiga Maris 28, 2023.
4. Aikawa, T., Takagi, H., Ishikawa, K. & Kuno, T. Myocardial Raunin da ke da girman troponin na zuciya da kuma mace-macen asibiti na COVID-19: fahimta daga meta-bincike. J. Med. Virol. 93, 51-55 (2021). https://doi.org/10.1002/jmv.26108
5. Patone, M., Mei, XW, Handunnetthi, L. et al. Hadarin myocarditis, pericarditis, da arrhythmias na zuciya da ke da alaƙa da rigakafin COVID-19 ko kamuwa da cutar SARS-CoV-2. Nat Med 28, 410-422 (2022). https://doi.org/10.1038/s41591-021-01630-0
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Paul Bourdon shi ne Farfesa na Lissafi, Janar Faculty, Jami'ar Virginia (Mai Ritaya); Tsohon, Cincinnati Farfesa na Lissafi, Jami'ar Washington & Lee
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